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PDE2 inhibitor 6

CAT: 0013-GTR19258541-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258541-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PDE2 inhibitor6 (Compound 1) is an orally active phosphodiesterase (PDE) inhibitor, effectively inhibiting PDE2A, PDE3B, and PDE10A2 with IC50 values of 0.95 nM, 6.17 μM (pIC50=5.21), and 87.1 nM (pIC50=7.06), respectively. It modulates AMPA receptor activity, enhances synaptic plasticity, and improves learning and memory in rat models. Furthermore, PDE2 inhibitor6 possesses blood-brain barrier permeability.
CAS Number
2097493-39-3
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Smiles
C[C@H]1[C@H] (C=2N3C (N=C (C (F) F) C2) =NC=N3) CN (C (=O) C=4C=C (C) N=C (C) C4) CC1
Molecular Formula
C20H22F2N6O
Molecular Weight
400.425
Storage Conditions
-20°C
Notes
For research use only.

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