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CPP12 (TFA)

CAT: 0804-HY-P10649A-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10649A-02Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CPP12 TFA is a small, amphiphilic, cyclic cell-penetrating peptide (CPP) in salt form. CPP12 TFA binds directly to plasma membrane phospholipids, enters mammalian cells via endocytosis, and is then efficiently released from endosomes. CPP12 TFA can be used for intracellular delivery of drugs and chemical probes[1].
UNSPSC
12352209
Target
Fluorescent Dye
Type
Peptides
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cpp12-tfa.html
Purity
98.69
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C([C@H](CC1=CC=C2C=CC=CC2=C1)NC([C@H](NC([C@@H](NC3=O)CC4=CC=CC=C4)=O)CC5=CC=CC=C5)=O)N[C@H](C(N[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H]3CCC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
Molecular Formula
C68H89F12N21O17
Molecular Weight
1700.55
References & Citations
[1]Qian Z, et al. Discovery and mechanism of highly efficient cyclic cell-penetrating peptides[J]. Biochemistry, 2016, 55 (18) : 2601-2612.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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