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VVD-699

CAT: 0013-GTR19258356-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258356-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VVD-699 is a covalent inhibitor of RAS-PI3K. It forms a covalent bond with cysteine at position 242 within the RAS-binding domain of PI3Kp110α, thereby obstructing the ability of RAS to activate PI3K. VVD-699 is capable of inhibiting the growth of tumors with RAS mutations and HER2 overexpression. It is applicable in research related to RAS mutation-associated cancers, such as those involving H358 lung cancer cells, A549 cells, and FaDu cells.
CAS Number
3055319-82-6
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
S (=O) (=O) (C1=C (C=C (OC) C=C1) C2=C (Cl) C=CC=C2) N3[C@H] (C) C[C@@] (C (N[C@@H] (/C=C\S (C) (=O) =O) C) =O) (F) CC3
Molecular Formula
C25H30ClFN2O6S2
Molecular Weight
573.097
Storage Conditions
-20°C
Notes
For research use only.

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