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AR antagonist 11

CAT: 0013-GTR19258220-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258220-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AR antagonist 11 (Compound c2) is a selective androgen receptor antagonist with an IC50 of 0.019 μM. It is also effective against the ARF877L/T878A mutant (IC50: 1.03 μM) . Additionally, AR antagonist 11 inhibits LNCaP cell proliferation and decreases PSA protein expression (IC50: 0.54 μM) . This compound is applicable in prostate cancer (PCa) research.
CAS Number
3005979-40-5
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Protein Biochemistry
Smiles
ClC1=CC=C ([C@H]2[C@@]3 ([C@] (C=4C=5C (C=CC4N2) =NC=CC5) (OCC3) [H]) [H]) C=C1
Molecular Formula
C20H17ClN2O
Molecular Weight
336.815
Storage Conditions
-20°C
Notes
For research use only.

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