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NMDAR antagonist 5

CAT: 0013-GTR19258154-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258154-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET) . It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM) . NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50> 100 μM; cardiac toxicity IC50= 24.5 μM) . It has antidepressant properties and is useful for depression research.
CAS Number
3038464-68-2
Field of Research
Neuroscience, Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Smiles
[C@]1 (CC2=C (CC1) NN=C2) (N3CCCC3) C4=CC=CC=C4
Molecular Formula
C17H21N3
Molecular Weight
267.369
Storage Conditions
-20°C
Notes
For research use only.

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