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RIPK1-IN-29

CAT: 0013-GTR19258103-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258103-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RIPK1-IN-29 (Compound 22) is a RIPK1 inhibitor with an IC50 of 6.9 nM. It exhibits anti-necroptotic apoptosis activity by inhibiting RIPK1. In a TNF-α induced inflammatory in vivo model, a 10 mg/kg dose of RIPK1-IN-29 can protect mice from hypothermia and death. This compound is suitable for research in the field of inflammatory diseases.
Field of Research
Cell Biology, Signal Transduction
Storage Conditions
-20°C
Notes
For research use only.

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