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IDO1/TDO-IN-8

CAT: 0013-GTR19258033-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258033-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IDO1/TDO-IN-8 (Compound CZ-17) is a dual IDO1 and TDO inhibitor capable of crossing the blood-brain barrier, with EC50 values of 0.33 μM and 1.78 μM, respectively. It modulates the kynurenine pathway of tryptophan metabolism, reducing the kynurenine/tryptophan ratio. IDO1/TDO-IN-8 has neuroprotective effects, alleviating motor dysfunction and improving depressive behavior, making it relevant for research into Parkinson's disease with comorbid depression.
Field of Research
Metabolism Research
Smiles
CC1=CC (C2=NC=CC3=C2NC4=CC=CC=C43) =C (C) S1
Molecular Formula
C17H14N2S
Molecular Weight
278.37
Storage Conditions
-20°C
Notes
For research use only.

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