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Bis-sulfone-PEG4-NHS ester

CAT: 0013-GTR19253506-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19253506-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bis-sulfone-PEG4-NHS ester is a bifunctional alkylating labeling reagent that selectively removes cysteine sulfur atoms from native disulfide bonds. These reagents perform bis-alkylation to attach both thiols from two cysteine residues, originating from reduced native disulfide bonds (such as interchain disulfide bonds in antibodies) . The reaction results in a covalent bond through a three-carbon bridge, maintaining the protein's structural integrity. The hydrophilic PEG spacer enhances its solubility in aqueous media.
CAS Number
2055047-19-1
Smiles
O=C (ON1C (=O) CCC1=O) CCOCCOCCOCCOCCNC (=O) C2=CC=C (C=C2) C (=O) C (CS (=O) (=O) C3=CC=C (C=C3) C) CS (=O) (=O) C4=CC=C (C=C4) C
Molecular Formula
C40H48N2O14S2
Molecular Weight
844.944
Storage Conditions
-20°C
Notes
For research use only.

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