Bis-sulfone NHS ester

• Description :

  Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Biochemical Assay Reagents

• Related Pathways :

  Others

• Field of Research :

  Others

• Purity :

  97.0

• Smiles :

  CC1=CC=C(S(=O)(CC(C(C2=CC=C(C(ON3C(CCC3=O)=O)=O)C=C2)=O)CS(=O)(C4=CC=C(C=C4)C)=O)=O)C=C1

• Molecular Formula :

  C29H27NO9S2

• Molecular Weight :

  597.66

• Precautions :

  H302, H315, H319, H335

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [899452-51-8]