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Bis-sulfone-PEG8-NHS ester

CAT: 0013-GTR19254179-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19254179-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bis-sulfone-PEG8-NHS ester is a bis-alkylating labeling agent that selectively removes cysteine sulfur atoms from native disulfide bonds. These agents achieve bis-alkylation by covalently bridging the two thiols from cysteine residues derived from reduced native disulfide bonds, such as interchain disulfide bonds in antibodies, through a three-carbon bridge while maintaining the integrity of the protein structure. The hydrophilic PEG spacer enhances solubility in aqueous media.
CAS Number
2363757-66-6
Smiles
O=C (ON1C (=O) CCC1=O) CCOCCOCCOCCOCCOCCOCCOCCOCCNC (=O) C2=CC=C (C=C2) C (=O) C (CS (=O) (=O) C3=CC=C (C=C3) C) CS (=O) (=O) C4=CC=C (C=C4) C
Molecular Formula
C48H64N2O18S2
Molecular Weight
1021.15
Storage Conditions
-20°C
Notes
For research use only.

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