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PIN1 degrader-1

CAT: 0013-GTR19250462-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250462-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PIN1degrader-1 (Compound 158H9) is a potent, covalent Pin1 inhibitor (IC50=21.5 nM) that binds Cys113, triggering protein destabilization and proteasomal degradation. This molecule is a valuable chemical probe for studying Pin1 biology in cancer research, demonstrating anti-proliferative effects in various cancer cell lines in vitro.
Smiles
C1CCN ([C@@H] (C1) C (=O) N[C@@H] (CC2=CNC3=CC=CC=C32) C (=O) N) C (=O) [C@H] (CC4=CNC5=C4C=CC (=C5) Cl) NC (=O) CCl
Molecular Formula
C30H32Cl2N6O4
Molecular Weight
611.519
Storage Conditions
-20°C
Notes
For research use only.

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