Products for Research Use Only

MAT2A-IN-20

CAT: 0013-GTR19250389-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250389-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MAT2A-IN-20 (Compound A49) is a potent, sub-50 nM inhibitor of methionine adenosyltransferase 2A (MAT2A) and a weaker inhibitor of human UGT1A1 (IC50 = 28.45 μM) . This small molecule has demonstrated antitumor efficacy in mouse models, supporting its use in oncology research for studying methionine metabolism and cancer cell proliferation in vitro and in vivo.
CAS Number
3018834-98-2
Field of Research
Epigenetics & Chromatin, Signal Transduction
Smiles
O=C1C (=NC=2C=NC (=NC2N1C3=CC=C (OC (F) F) C=C3) OCC) C=4C=CC=5N=C (N (C5C4) C) C (O) (C) C
Molecular Formula
C26H24F2N6O4
Molecular Weight
522.503
Storage Conditions
-20°C
Notes
For research use only.