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VHF 543, amine

CAT: 0013-GTR19249652-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249652-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VHF 543, Amine is a high-affinity binder (Kd = 31 nM) for the DCAF1 WD40 domain, facilitated by its primary amine handle for conjugation. This tool compound is utilized in vitro for targeted protein degradation research, particularly in probing Cullin-RING E3 ubiquitin ligase complexes and their substrate recruitment mechanisms.
CAS Number
3053860-67-3
Smiles
O=C (N1CCN (C=2C=CC3=C (N=C (N=C3NCCN) C4 (C5=CC=C (Cl) C=C5) CCCCC4) C2) CC1) C
Molecular Formula
C28H35ClN6O
Molecular Weight
507.07
Storage Conditions
-20°C
Notes
For research use only.

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