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TLR7 agonist 29

CAT: 0013-GTR19249636-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249636-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TLR7 agonist 29 (Compound 1) is a potent small molecule activator of human and mouse TLR7, with EC50 values of 5.2 nM and 48.2 nM, respectively. It induces immune activation in BMDMs and tumor myeloid cells, upregulating PD-L1, CD86, and IFN-α, and is suitable for use as an ADC payload in immunotherapy research.
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology
Molecular Formula
C20H27N7O2
Molecular Weight
397.47
Storage Conditions
-20°C
Notes
For research use only.

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