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TLR7 agonist 22

CAT: 0013-GTR19262747-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19262747-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TLR7 agonist22 (Compound 11a) is a selective TLR7 agonist with an IC50 value of 25.86 μM. It inhibits the secretion of cell HBsAg and effectively activates TLR7, inducing the release of TLR7-regulated cytokines IL-12, TNF-α, and IFN-α in human PBMC cells. TLR7 agonist22 shows promise for developing novel immunomodulatory drugs in HBV research.
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology
Storage Conditions
-20°C
Notes
For research use only.

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