Products for Research Use Only

HPK1-IN-54

CAT: 0013-GTR19241066-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241066-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HPK1-IN-54 is a highly selective and potent HPK1 inhibitor (IC50=2.67 nM) that enhances T cell function. It demonstrates significant oral antitumor efficacy in murine models like CT26 colon cancer, both as a monotherapy and synergistically with anti-PD-1 treatment, making it a valuable tool for immuno-oncology research.
CAS Number
3048537-48-7
Field of Research
Signal Transduction
Smiles
O=C1NCC2=C (C=CC (NC=3N=C4C (=CC3) C5 (N (C4) CCN6CCOCC6) CCOCC5) =C12) C7=CN=C8C=C (F) C=CN87
Molecular Formula
C32H34FN7O3
Molecular Weight
583.66
Storage Conditions
-20°C
Notes
For research use only.