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GGFG-PAB-MMAE

CAT: 0013-GTR19239653-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239653-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GGFG-PAB-MMAE (Comp 58054-1) is an antibody-drug conjugate (ADC) linker-payload featuring the protease-cleavable valine-citrulline linker GGFG-PAB conjugated to the cytotoxic agent MMAE, a potent tubulin inhibitor. This conjugate is widely used in ADC research for targeted cancer therapy development, enabling the study of drug delivery and efficacy in both in vitro and in vivo models.
CAS Number
3049886-19-0
Field of Research
Signal Transduction
Smiles
[C@H] ([C@H] (C (N[C@@H] ([C@@H] (O) C1=CC=CC=C1) C) =O) C) (OC) [C@]2 (N (C (C[C@H] ([C@@H] (N (C ([C@@H] (NC ([C@@H] (N (C (OCC3=CC=C (NC (CNC ([C@H] (CC4=CC=CC=C4) NC (CNC (CN) =O) =O) =O) =O) C=C3) =O) C) [C@@H] (C) C) =O) C (C) C) =O) C) [C@H] (CC) C) OC) =O) CCC2) [H]
Molecular Formula
C62H92N10O13
Molecular Weight
1185.45
Storage Conditions
-20°C
Notes
For research use only.

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