Products for Research Use Only

STGFBR3 antagonist 1

CAT: 0013-GTR19238484-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238484-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STGFBR3 antagonist 1 (Compound p24) is a dual-pathway modulator that activates TGF-β signaling while suppressing NF-κB, demonstrating anti-inflammatory and neuroprotective effects in vitro, such as inhibiting LPS-induced NO release in BV2 microglia (IC50 = 0.52 μM) . Its ability to enhance blood-brain barrier permeability supports its research utility in neurodegenerative disease models, including Alzheimer's.
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Storage Conditions
-20°C
Notes
For research use only.