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STGFBR3 antagonist 1

CAT: 0931-T88867-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88867-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
TGF-beta/Smad, Others
Related Pathways
Others, Stem Cells
Bioactivity
STGFBR3 antagonist 1 (Compound p24) is an antagonist of soluble transforming growth factor β receptor 3 (sTGFBR3) that activates the TGF-β signaling pathway while inhibiting the IκBα/NF-κB signaling pathway. It inhibits the release of NO induced by LPS in BV2 cells with an IC50 of 0.52 μM. sTGFBR3 antagonist 1 exhibits anti-inflammatory and neuroprotective activities and can enhance the permeability of the blood-brain barrier (BBB) . This compound is applicable in research related to Alzheimers disease.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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