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DOTA.SA.FAPi TFA

CAT: 0013-GTR19238408-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238408-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DOTA.SA.FAPi TFA is a bifunctional chelator combining a squaric acid derivative with the FAP inhibitor UAMC1110. It potently inhibits fibroblast activation protein (FAP; IC50 = 0.9 nM) and targets prolyl endopeptidase (PREP; IC50 = 5.4 μM) . When radiolabeled with 68Ga, it functions as a PET tracer for imaging FAP-expressing cancers in preclinical research.
Field of Research
Immunology & Inflammation, Metabolism Research, Protein Biochemistry
Storage Conditions
-20°C
Notes
For research use only.

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