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KRAS inhibitor-25

CAT: 0013-GTR19238310-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238310-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KRAS inhibitor-25 (compound 151a) is a potent pyrido[2,3-d]pyrimidine-based inhibitor effective against KRAS wild-type and mutants including G12V and G12R, with IC50 values under 100 nM. It is a valuable chemical probe for in vitro biochemical and cellular studies targeting oncogenic KRAS-driven cancers.
CAS Number
3030577-05-7
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (OC1=NC2=C3C (=N1) C (F) =C (N=C3) C=4C (=C (Cl) C=C (O) C4) CCCCCCC5 (O) CN2CCC5) [C@@]67N (C[C@H] (F) C6) CCC7
Molecular Formula
C32H38ClF2N5O3
Molecular Weight
614.13
Storage Conditions
-20°C
Notes
For research use only.

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