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LL-K12-18

CAT: 0013-GTR19238117-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238117-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LL-K12-18 is a molecular glue that stabilizes the interaction between CDK12 and DDB1, leading to Cyclin K degradation. This compound suppresses transcription and proliferation in cancer cells, serving as a valuable chemical probe for studying CDK12/cyclin K biology and targeted protein degradation in oncology research.
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.08% (May vary between batches)
Smiles
CCN1C2=NC (N3CCN (C (CN (CC) CC) =O) CC3) =NC (NCC4=NC5=CC (Cl) =C (Cl) C=C5N4) =C2N=C1
Molecular Formula
C25H32Cl2N10O
Molecular Weight
559.49
Storage Conditions
-20°C
Notes
For research use only.

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