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EGFR mutant

CAT: 0013-GTR18146103Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18146103Size:100 µL
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Description
Mouse monoclonal antibody to EGFR mutant (L858R)
Product Name Alternative
ERBB; HER1; mENA; ERBB1; PIG61
UniProt
P00533
Reactivity
Human
Immunogen
Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. Coli.
Target
Disease
Clonality
Monoclonal
Clone
B7I1D7
Conjugation
Unconjugated
Field of Research
Cell Biology
Concentration
1mg/ml
Dilution
IHC: 1/200 - 1/1000; FCM: 1/200 - 1/400; ELISA: 1/10000
Molecular Weight
175kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, IHC, WB
Host or Source
Mouse
Preservative
Ascitic fluid containing 0.03% sodium azide.
Isotype
Mouse IgG1
Entrez
1956

UniProtKB · P00533

Epidermal growth factor receptor

EGFR_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00533
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
EGFR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
O00688, O00732, P06268, Q14225, Q68GS5, Q92795, Q9BZS2, Q9GZX1, Q9H2C9, Q9H3C9, Q9UMD7, Q9UMD8, Q9UMG5
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneEndoplasmic reticulumEndosomeGolgi apparatusMembraneNucleusSecreted

Molecular function

Developmental proteinHost cell receptor for virus entryKinaseReceptorTransferaseTyrosine-protein kinase

Disease

Disease variantProto-oncogene

PTM

Disulfide bondGlycoproteinHydroxylationIsopeptide bondLipoproteinMethylationPalmitatePhosphoproteinUbl conjugation

Biological process

Host-virus interaction

Domain

RepeatSignalTransmembraneTransmembrane helix

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