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LRRK2-IN-14

CAT: 0013-GTR19235028-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235028-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LRRK2-IN-14 (Compound 8) is a potent, brain-penetrant, and orally bioavailable inhibitor of LRRK2, demonstrating an IC50 of 6.3 nM against the G2019S mutant. It is a valuable research tool for investigating LRRK2 kinase function in cellular models and in vivo studies of Parkinson's disease, with noted hERG activity (IC50 = 22 μM) .
CAS Number
2942328-06-3
Field of Research
Cell Biology
Smiles
O (C) C1=C2NC=3NC (C (C (F) (F) F) =CN3) =NCCCN (C) C (=O) C (=C2) C=C1
Molecular Formula
C17H18F3N5O2
Molecular Weight
381.35
Storage Conditions
-20°C
Notes
For research use only.

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