Products for Research Use Only
RegisterLogin

NLRP3-IN-25

CAT: 0013-GTR19234895-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19234895-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NLRP3-IN-25 (compound 32) is a potent, orally bioavailable NLRP3 inhibitor with an IC50 of 21 nM for IL-1β secretion in THP-1 cells. It demonstrates anti-inflammatory efficacy in vivo by reducing renal injury in a mouse model of doxorubicin-induced glomerulonephritis, supporting research into NLRP3-driven inflammatory diseases.
CAS Number
2660230-90-8
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
N (C1=CC (C (F) (F) F) =CC=C1C) C2=NC (C (NS (=O) (=O) N3CCCOCC3) =O) =CO2
Molecular Formula
C17H19F3N4O5S
Molecular Weight
448.42
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR18900569-01NLRP3 peptide
GTR19243684-01NLRP3-IN-13
GTR19243206-01NLRP3-IN-71
GTR19238896-01NLRP3-IN-53
GTR19238804-01NLRP3-IN-49
GTR19237514-01NLRP3-IN-44
GTR19171614-01NLRP3-IN-9
GTR19274950-01NLRP3-IN-86
GTR19273326-01NLRP3-IN-84
GTR19263241-01NLRP3-IN-81

Alternative Products

CatalogName
BA6050-10NLRP3-IN-25
QY-E06005Human NLRP3 Inflammasome (NLRP3)
MBS8534011-01NLRP3

Popular Products