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PRMT5-IN-41

CAT: 0013-GTR19237323-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237323-01Size:25 mg
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Description
PRMT5-IN-41 (compound 130) is an orally bioavailable small molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) . This compound also demonstrates hERG channel inhibition with an IC50 of 1.36 μM, a consideration for cardiac safety profiling. It is a useful research tool for investigating PRMT5 biology and oncology in both cellular and animal models.
CAS Number
3034034-32-4
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
C (N (C) [C@H]1C=2C (OC1) =CC (C (C (F) (F) F) (F) F) =CC2) (=O) C=3C=C4N5C (C (N) =NC4=CC3) =CN=C5
Molecular Formula
C22H16F5N5O2
Molecular Weight
477.39
Storage Conditions
-20°C
Notes
For research use only.

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