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NH2-methylpropanamide-Exatecan TFA

CAT: 0013-GTR19231353-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19231353-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Exatecan TFA is a methylpropanamide-modified derivative of the cytotoxin Exatecan, functioning as a potent DNA topoisomerase I inhibitor with an IC50 of 2.2 μM. It is widely used in the synthesis of antibody-drug conjugates (ADCs) for targeted cancer therapy research, applicable in both in vitro biochemical assays and in vivo preclinical studies.
CAS Number
1817857-35-4
Field of Research
Immunology & Inflammation; Pharmacology & Drug Discovery, Molecular Biology
Smiles
C (C (O) =O) (F) (F) F.N (C ([C@H] (CN) C) =O) [C@@H]1C2=C3C (C=4N (C3) C (=O) C5=C (C4) [C@] (CC) (O) C (=O) OC5) =NC=6C2=C (CC1) C (C) =C (F) C6
Molecular Formula
C30H30F4N4O7
Molecular Weight
634.58
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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MBS5819560NH2-methylpropanamide-Exatecan TFA
HY-156686-01NH2-methylpropanamide-Exatecan (TFA)
HY-145397-01(4-NH2) -Exatecan
MBS5800449(4-NH2)-Exatecan
HY-145397S-01(4-NH2) -Exatecan-d5
HY-145397A(R) - (4-NH2) -Exatecan
HY-160885NH2-Gly-PAB-Exatecan-D-glucuronic acid
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