Products for Research Use Only
RegisterLogin

Gap 27

CAT: 0804-HY-P0139-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P0139-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Gap 27, a synthetic connexin43 mimetic peptide, is a gap junction inhibitor. Gap 27 possesses conserved sequence homology to a portion of the second extracellular loop leading into the fourth transmembrane connexin segment[1][2].
CAS Number
198284-64-9
UNSPSC
12352209
Target
Connexin; Gap Junction Protein
Type
Peptides
Related Pathways
Cytoskeleton
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Gap_27.html
Purity
99.90
Solubility
DMSO : 22.22 mg/mL (ultrasonic; adjust pH to 2 with 1 M HCl) |H2O : ≥ 33.33 mg/mL
Smiles
OC[C@H](N)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C60H101N15O17
Molecular Weight
1304.53
References & Citations
[1]Ilvesaro J, et al. Connexin-mimetic peptide Gap 27 decreases osteoclastic activity. BMC Musculoskelet Disord. 2001;2:10.|[2]Edwards G, et al. Role of gap junctions in the responses to EDHF in rat and guinea-pig small arteries. Br J Pharmacol. 1999 Dec;128 (8) :1788-94.|[3]Chaytor AT, e t al. Central role of heterocellular gap junctional communication in endothelium-dependent relaxations of rabbit arteries. J Physiol. 1998 Apr 15;508 (Pt 2) :561-73.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

Related Products

CatalogName
HY-178334GAP-1173149
HY-P1082-01Gap 26
HY-148108-01AChE-IN-27
HY-178812PI3Kα-IN-27
HY-176413SDH-IN-27
HY-172900AKT-IN-27
HY-142690HDAC-IN-27
HY-P3508-01PNC-27
HY-142677PI3K-IN-27
HY-161179TRK-IN-27

Alternative Products

CatalogName
CN-A038-500GMAgar, Micropropagation - Type I (Gracilaria)
M2302-20HPhaseShield™ Gel Tubes, Heavy (200x 2ml)
M2302-20LPhaseShield™ Gel Tubes, Light (200x 2ml)
RHD55901Anti-PTGS1 Antibody (R1S27)
RHD55804Anti-TCEA1 Antibody (R1S24)
E-KAB-0614Porcine IL-2 Antibody Pair Set
RHD55803Anti-TCEA1 Antibody (R1S23)
PKSH030904Recombinant Human Purine nucleoside phosphorylase/PNP Protein (His Tag)
PKSH031350Recombinant Human Ficolin-1/Ficolin-A/FCN1 Protein (His Tag)
RHD55701Anti-FBLN1 Antibody (R1S21)

Popular Products