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I-287

CAT: 0013-GTR19231015-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19231015-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
I-287 is a selective, orally bioavailable PAR2 negative allosteric modulator that inhibits Gαq and Gα12/13 signaling. It has demonstrated efficacy in reducing inflammatory pain in murine CFA models, supporting its use as a research tool for studying inflammation, immune responses, and protease-activated receptor pathways in both in vitro and in vivo settings.
CAS Number
2014368-93-3
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
C (C) (C) (C) C1=C2C (=NC (=C1) C3=CC (F) =C (Cl) C=C3) C=C (C (=O) N4C (C) (C) CN (CC4) C5=CC=C (C (O) =O) C=N5) O2
Molecular Formula
C30H30ClFN4O4
Molecular Weight
565.04
Storage Conditions
-20°C
Notes
For research use only.

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