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CRBN ligand-287

CAT: 0013-GTR19276064-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19276064-01Size:10 mg
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Description
CRBN ligand-287 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), utilized for recruiting the cereblon protein. This compound can link with a target protein ligand using a linker to form a PROTAC.
CAS Number
2933136-78-6
Smiles
O=C1NC (=O) C (C2=CC=C (O) C (=C2) C (F) (F) F) CC1
Molecular Formula
C12H10F3NO3
Molecular Weight
273.21
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

3-[4-Hydroxy-3-(trifluoromethyl)phenyl]piperidine-2,6-dione
CAS Number2933136-78-6
PubChem CID168902040
IUPAC Name3-[4-hydroxy-3-(trifluoromethyl)phenyl]piperidine-2,6-dione
Molecular FormulaC12H10F3NO3
Molecular Weight273.21
XLogP1.5
Topological Polar Surface Area66.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Heavy Atom Count19
Formal Charge0
Complexity383
SMILES
C1CC(=O)NC(=O)C1C2=CC(=C(C=C2)O)C(F)(F)F
InChI
InChI=1S/C12H10F3NO3/c13-12(14,15)8-5-6(1-3-9(8)17)7-2-4-10(18)16-11(7)19/h1,3,5,7,17H,2,4H2,(H,16,18,19)
InChIKey
KHZKBUXUYWZTCO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-[4-Hydroxy-3-(trifluoromethyl)phenyl]piperidine-2,6-dione
CAS: 2933136-78-6
CID: 168902040
Formula: C12H10F3NO3
MW: 273.21
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight273.21
XLogP31.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Exact Mass273.06127767
Monoisotopic Mass273.06127767
Topological Polar Surface Area66.4 Ų
Heavy Atom Count19
Formal Charge0
Complexity383
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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