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SHP2-IN-22

CAT: 0013-GTR19230836-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230836-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHP2-IN-22 is a potent allosteric SHP2 inhibitor with an IC50 of 17.7 nM. It effectively inhibits proliferation, migration, and invasion in KRAS-mutant MIA PaCa-2 pancreatic cancer cells in vitro, making it a valuable tool for studying oncogenic signaling in KRAS-driven cancers.
CAS Number
2802453-88-7
Field of Research
Metabolism Research, Signal Transduction
Smiles
NC=1C (=NC=C (N1) N2CCN (C (NC3=CC (OC) =C (C#N) C=C3) =N) CC2) C4=C (Cl) C (Cl) =CC=C4
Molecular Formula
C23H22Cl2N8O
Molecular Weight
497.38
Storage Conditions
-20°C
Notes
For research use only.

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