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SHP2-IN-23

CAT: 0013-GTR19234643-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234643-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SHP2-IN-23 (compound 30) is a potent, orally bioavailable SHP2 inhibitor with an IC50 of 38 nM. It effectively blocks downstream ERK phosphorylation (IC50 = 5 nM) and demonstrates robust in vivo efficacy, making it a valuable chemical probe for cancer research, particularly in studying RTK and MAPK signaling pathways.
CAS Number
2415989-91-0
Field of Research
Metabolism Research, Signal Transduction
Smiles
N[C@H]1C2 (CC=3C1=CC=CN3) CCN (CC2) C4=NC5=C (N=C4) N=C (SC=6C (Cl) =C (N) N=CC6) C=C5
Molecular Formula
C24H23ClN8S
Molecular Weight
491.01
Storage Conditions
-20°C
Notes
For research use only.

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