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YXG-158

CAT: 0013-GTR19230482-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230482-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YXG-158 (Compound 23-h) is an orally bioavailable small molecule that degrades the androgen receptor (DC50 = 1.28 μM) and inhibits CYP17A1 (IC50 = 100 nM) . It is a candidate research tool for investigating therapeutic strategies against castration-resistant and enzalutamide-resistant prostate cancer models.
CAS Number
2952994-34-0
Field of Research
Metabolism Research
Smiles
C[C@@]12[C@] ([C@]3 ([C@@] ([C@]4 (C) C (=CC3) C[C@@H] (NC (=O) C5=CC=C (F) C=C5) CC4) (CC1) [H]) [H]) (CC=C2N6C=C (C) N=C6) [H]
Molecular Formula
C30H36FN3O
Molecular Weight
473.62
Storage Conditions
-20°C
Notes
For research use only.

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