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JNK-IN-14

CAT: 0013-GTR19230295-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230295-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNK-IN-14 is a potent and selective JNK inhibitor with single-digit nanomolar IC50 values against JNK1, JNK2, and JNK3 isoforms. It demonstrates robust cellular activity by inducing apoptosis, causing G2/M phase arrest, and modulating autophagy-related proteins like beclin-1 in leukemia cell models, showing superior potency to SP600125. This inhibitor is a valuable chemical probe for researching JNK signaling in oncology, neurology, and cellular stress responses both in vitro and in vivo.
Field of Research
Metabolism Research, Signal Transduction
Molecular Formula
C27H31N5O4S
Molecular Weight
521.63
Storage Conditions
-20°C
Notes
For research use only.

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