RTIOXA-43

CAT: 0013-GTR19234682-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19234682-01Size:10 mg

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Description

RTIOXA-43 is a dual orexin receptor (OX1R/OX2R) agonist used in research to promote wakefulness and reduce sleep attacks. It is a valuable tool for in vitro and in vivo studies investigating narcolepsy, sleep/wake neurobiology, and orexin signaling pathways.

CAS Number

2832067-72-6

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.17% (May vary between batches)

Solubility

DMSO:80 mg/mL (120.52 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.97 mM)

Smiles

COc1ccc (cc1S (=O) (=O) Nc1cccc (NCCNC (=O) c2cccc (C) c2) c1) -c1cccc (c1) C (=O) N (C) Cc1ccncc1

Molecular Formula

C37H37N5O5S

Molecular Weight

663.79

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

Rtioxa-43

CAS Number	2832067-72-6
PubChem CID	166625259
IUPAC Name	N-[2-[3-[[2-methoxy-5-[3-[methyl(pyridin-4-ylmethyl)carbamoyl]phenyl]phenyl]sulfonylamino]anilino]ethyl]-3-methylbenzamide
Molecular Formula	C37H37N5O5S
Molecular Weight	663.8
XLogP	5.2
Topological Polar Surface Area	138
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	13
Heavy Atom Count	48
Formal Charge	0
Complexity	1130

SMILES

CC1=CC(=CC=C1)C(=O)NCCNC2=CC(=CC=C2)NS(=O)(=O)C3=C(C=CC(=C3)C4=CC(=CC=C4)C(=O)N(C)CC5=CC=NC=C5)OC

InChI

InChI=1S/C37H37N5O5S/c1-26-7-4-9-30(21-26)36(43)40-20-19-39-32-11-6-12-33(24-32)41-48(45,46)35-23-29(13-14-34(35)47-3)28-8-5-10-31(22-28)37(44)42(2)25-27-15-17-38-18-16-27/h4-18,21-24,39,41H,19-20,25H2,1-3H3,(H,40,43)

InChIKey

WIANBLHLJZGLLG-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 2832067-72-6

CID: 166625259

Formula: C37H37N5O5S

MW: 663.8

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	663.8
XLogP3	5.2
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	13
Exact Mass	663.25154047
Monoisotopic Mass	663.25154047
Topological Polar Surface Area	138 Å²
Heavy Atom Count	48
Formal Charge	0
Complexity	1130
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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Alternative Products

Catalog	Name
T87345-01	RTIOXA-43
G8990-10H	Growth Associated Protein 43 (GAP-43)
C8208-10	FM1-43
BA2890-5	INI-43
BA2806-1	SC-43
BA7092-1	HSD17B13-IN-43
HY-174386	STAT3-IN-43
575601	FM1 43
HY-147966	HDAC-IN-43
T210097-01	HDAC6-IN-43

RTIOXA-43

Chemical Information

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