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ERD-3111

CAT: 0013-GTR19230896-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19230896-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ERD-3111 (Compound 44) is a potent, orally bioavailable PROTAC that selectively degrades ERα with a DC50 of 0.5 nM. It demonstrates robust anti-tumor activity in vivo against both wild-type and ESR1-mutant ER+ breast cancer models, making it a valuable chemical probe for investigating endocrine resistance mechanisms.
CAS Number
2832865-25-3
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (C (F) F) N1[C@@H] (C2=C (C3=C (C=C2) NN=C3) C[C@H]1C) C4=C (F) C=C (C=C4F) N5CCC6 (CC5) CCN (C (CN7CC=8C (C7) =CC9=C (C8) C (=O) N (C9=O) C%10C (=O) NC (=O) CC%10) =O) CC6
Molecular Formula
C45H46F4N8O5
Molecular Weight
854.89
Storage Conditions
-20°C
Notes
For research use only.

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