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ERD-308

CAT: 0013-GTR19204347-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204347-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ERD-308 is a potent PROTAC degrader of estrogen receptor (ER), achieving >95% degradation at 5 nM with low DC50 values in ER+ breast cancer cell lines. It serves as a critical research tool for investigating targeted protein degradation in both in vitro and in vivo models of hormone receptor-positive cancers.
CAS Number
2320561-35-9
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Smiles
C (=O) (C1=C (SC=2C1=CC=C (O) C2) C3=CC=C (O) C=C3) C4=CC=C (OCCN (CCCCCOCC (N[C@H] (C (=O) N5[C@H] (C (N[C@@H] (C) C6=CC=C (C=C6) C=7SC=NC7C) =O) C[C@@H] (O) C5) [C@] (C) (C) C) =O) CC) C=C4
Molecular Formula
C55H65N5O9S2
Molecular Weight
1004.26
Storage Conditions
-20°C
Notes
For research use only.

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