Products for Research Use Only
RegisterLogin

ERD-12310A

CAT: 0804-HY-164924Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-164924Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ERD-12310A is a PROTAC targeting Estrogen Receptor α (ERα) with a ED50 value of 47 pM. ERD-12310A has oral activity. ERD-12310A is composed of PROTAC target protein ligand ER ligand-4 (red part), E3 ligase ligand (S) -Deoxy-thalidomide (HY-168055) (blue part). ERD-12310A can be used in the research of ER+ breast cancer[1].
UNSPSC
12352005
Target
Estrogen Receptor/ERR; PROTACs
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/erd-12310a.html
Smiles
O=C(N1)[C@H](CCC1=O)N(C2=O)CC3=C2C=CC4=C3OCC45CCN(CC5)C[C@H]6COC7(CC6)CCN(CC7)C8=CC=C(C=C8)[C@H]9[C@H](CCC%10=C9C=CC(O)=C%10)C%11=CC=CC=C%11
Molecular Formula
C51H56N4O6
Molecular Weight
821.01
References & Citations
[1]Rohan Kalyan Rej, et al. Discovery of ERD-12310A as an Exceptionally Potent and Orally Efficacious PROTAC Degrader of Estrogen Receptor α (ERα) . J Med Chem. 2024 Nov 25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-169367ERD-1233
HY-128600-01ERD-308
HY-149480-01ERD-3111
HY-116623A-123189
HY-121767-01PD 123177
HY-126973BI-1230
HY-165616NS 1231
HY-R00127A-01Hsa-miR-1231 agomir
HY-RI00127-01Hsa-miR-1231 inhibitor
HY-R00127-01Hsa-miR-1231 mimic

Alternative Products

CatalogName
GTR19241298-01ERD-12310A
BA9215-5ERD-308
VSD56135-01ERD 308
MBS5820485ERD-3111
GTR19240614-01ERD-1233
A18446-100ERD-308 100mg
A18446-50ERD-308 50mg
A18446-25ERD-308 25mg
A18446-10ERD-308 10mg
A18446-5ERD-308 5mg

Popular Products