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CDK9 Antagonist-1

CAT: 0013-GTR19223534-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19223534-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK9 Antagonist-1 (compounds 11c) is a potent and selective PROTAC-based CDK9 degrader, demonstrating an IC50 of 17 μM in MCF-7 breast cancer cells. This compound, which utilizes a wogonin-derived linker to engage the CRBN E3 ligase, is a valuable chemical probe for investigating CDK9-dependent transcription in oncology and molecular pharmacology research.
Field of Research
Epigenetics & Chromatin; Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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