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CDK9/PARP-IN-1

CAT: 0931-T205731-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T205731-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3032818-67-7
Target
CDK, PARP
Related Pathways
Chromatin/Epigenetic, Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Bioactivity
CDK9/PARP-IN-1 (compound 37) is an inhibitor of CDK9 and PARP. It demonstrates IC50 values of 118 nM for CDK9 and 107 nM for PARP1. This compound exhibits a broad-spectrum anti-proliferative effect across various cancer cell lines.
Smiles
O=C1NN=C(C=2C=CC=CC12)CC3=CC=C(F)C(=C3)C(=O)N4CCN(CC=5C=CN=C(C5)NC6=NC=NC(=C6)C=7C=CC(F)=CC7OCC)CC4
Molecular Formula
C38H34F2N8O3
Molecular Weight
688.725
Shipping Conditions
Ice Packs
Storage Temperature
-20°C