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PROTAC BRD4 Degrader-12

CAT: 0013-GTR19221487-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221487-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC BRD4 Degrader-12 (compound 9c) is a heterobifunctional degrader that effectively targets BRD4 in cancer research. It demonstrates potent in vitro activity in PC3 prostate cancer cells, with sub-nanomolar DC50 values, and has been utilized in antibody-drug conjugate (ADC) platforms for targeted protein degradation studies.
CAS Number
2417370-90-0
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
CC (OC (=O) O[C@@H]1C[C@H] (N (C1) C (=O) [C@@H] (NC (=O) CCCCCCCCCCNC (=O) c1cc2N (Cc3c[nH]c4c3c (cn (C) c4=O) -c2cc1CS (C) (=O) =O) c1ncc (F) cc1F) C (C) (C) C) C (=O) NCc1ccc (cc1) -c1scnc1C) C (C) SS (C) (=O) =O
Molecular Formula
C62H77F2N9O12S4
Molecular Weight
1306.58
Storage Conditions
-20°C
Notes
For research use only.

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