Products for Research Use Only

RIPK1-IN-16

CAT: 0013-GTR19219214-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19219214-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RIPK1-IN-16 is a potent, orally bioavailable small molecule inhibitor of RIPK1. It blocks RIPK1-mediated necroptosis, providing protection in murine models of TNF-driven systemic inflammatory response syndrome (SIRS) and sepsis, making it a valuable tool for studying inflammatory and cell death pathways in vivo and in vitro.
CAS Number
2561431-77-2
Field of Research
Cell Biology, Signal Transduction
Smiles
CN1C=2C (OC[C@H] (NC (=O) C=3NC (CC4=CC=CC=C4) =NN3) C1=S) =CC=CC2
Molecular Formula
C20H19N5O2S
Molecular Weight
393.46
Storage Conditions
-20°C
Notes
For research use only.