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PROTAC EGFR degrader 7 diTFA

CAT: 0013-GTR19218638-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218638-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC EGFR degrader 7 is a potent and selective CRBN-based degrader of the EGFRL858R/T790M mutant (DC50 = 13.2 nM) . It demonstrates robust anti-proliferative activity (IC50 = 46.82 nM in NCI-H1975 cells), induces apoptosis and G2/M arrest, supporting its application in targeted protein degradation and NSCLC research.
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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