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Thalidomide-NH-CH2-COOH

CAT: 0013-GTR19216483-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19216483-01Size:100 mg
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Description
Thalidomide-NH-CH2-COOH is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker. (In Vitro) :PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
CAS Number
927670-97-1
Product Name Alternative
(2- (2,6-Dioxopiperidin-3-yl) -1,3-dioxoisoindolin-4-yl) glycine | 2-[[2- (2,6-dioxopiperidin-3-yl) -1,3-dioxoisoindol-4-yl]amino]acetic acid
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 50 mg/mL (150.93 mM)
Smiles
OC (CNc1cccc (C (N2C (CCC (N3) =O) C3=O) =O) c1C2=O) =O
Molecular Formula
C15H13N3O6
Molecular Weight
331.28
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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