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Thalidomide-NH- (CH2) 2-NH2 TFA

CAT: 0013-GTR19218928Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19218928Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thalidomide-NH- (CH2) 2-NH2 TFA is a key alkyl-modified Cereblon (CRBN) ligand for constructing PROTAC degraders. It serves as a pivotal intermediate in synthesizing heterobifunctional molecules, such as those targeting SHP2, for targeted protein degradation research in both cellular and in vivo models.
CAS Number
1957235-67-4
Field of Research
Cell Biology, Immunology & Inflammation; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery
Smiles
NCCNC1=C2C (=O) N (C3C (=O) NC (=O) CC3) C (=O) C2=CC=C1.OC (=O) C (F) (F) F
Molecular Formula
C17H17F3N4O6
Molecular Weight
430.34
Storage Conditions
-20°C
Notes
For research use only.

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