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ALK inhibitor 2

CAT: 0804-HY-15358-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15358-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ALK inhibitor 2 (compound 18) is a potent pyrimidin ALK inhibitor. ALK inhibitor 2 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=37 nM) and focal adhesion kinase (FAK; IC50=5 nM) [1].
CAS Number
761438-38-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Anaplastic lymphoma kinase (ALK) ; FAK
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ALK-inhibitor-2.html
Concentration
10mM
Purity
99.72
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=S(C1=C(NC2=C(Cl)C=NC(NC3=C(OC)C=C(N4CCN(C)CC4)C=C3)=N2)C=CC=C1)(NC)=O
Molecular Formula
C23H28ClN7O3S
Molecular Weight
518.03
Precautions
H302, H315, H319, H335
References & Citations
[1]Jon E Hawkinson, et al. Potent Pyrimidine and Pyrrolopyrimidine Inhibitors of Testis-Specific Serine/Threonine Kinase 2 (TSSK2) . ChemMedChem. 2017 Nov 22;12 (22) :1857-1865.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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