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A2AR-antagonist-1

CAT: 0013-GTR19212653-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19212653-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A2AR-antagonist-1 is an orally bioavailable, potent A2A receptor antagonist (IC50 = 29 nM) with demonstrated metabolic stability. It exhibits anti-tumor activity by reversing T-cell suppression, downregulating LAG-3/TIM-3 and upregulating effector molecules like IFN-γ and Granzyme B, making it a valuable tool for immuno-oncology research.
CAS Number
2922920-71-4
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
CC1=C (C=CC=C1C2=NC (=NC (=C2) C3=CC (=O) N (C=C3) CC4=CC (=CC=C4) C (C) (C) O) N) C#N
Molecular Formula
C27H25N5O2
Molecular Weight
451.52
Storage Conditions
-20°C
Notes
For research use only.

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