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A2AR-agonist-1

CAT: 0804-HY-18776-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-18776-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A2AR-agonist-1 is a potent A2AR agonist and ENT1 inhibitor with Ki of 4.39 and 3.47 for A2AR and ENT1.
CAS Number
41552-95-8
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/A2AR-agonist-1.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C3=C(N=C2)C(NCCC4=CNC5=C4C=CC=C5)=NC=N3)O1
Molecular Formula
C20H22N6O4
Molecular Weight
410.43
References & Citations
[1]Chen JB, et al. Design and synthesis of novel dual-action compounds targeting the adenosine A (2A) receptor and adenosine transporter for neuroprotection. ChemMedChem. 2011 Aug 1;6 (8) :1390-1400.|[2]Lin Yun-Lian, et al. Dual-action compounds targeting adenosine A2A receptor and adenosine transporter for prevention and treatment of neurodegenerative diseases. From PCT Int. Appl. (2012), WO 2012064340 A1 20120518.|[3]Chen, Chih-Cheng, et al. Methods and compositions for treating pain. From PCT Int. Appl. (2013), WO 2013120078 A1 20130815.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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A21063-500A2AR-agonist-1 500mg
A21063-10A2AR-agonist-1 10mg
A21063-2A2AR-agonist-1 2mg
A21063-1A2AR-agonist-1 1mg
A21063-100A2AR-agonist-1 100mg
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A21063-25A2AR-agonist-1 25mg
A21063-5A2AR-agonist-1 5mg

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