Products for Research Use Only
RegisterLogin

CLK8

CAT: 0013-GTR19211992Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19211992Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CLK8 is a selective small molecule inhibitor that disrupts the CLOCK:BMAL1 complex, attenuating circadian transcriptional activity. It is a valuable research tool for investigating circadian rhythm mechanisms and related disorders in both cellular (in vitro) and animal (in vivo) models.
CAS Number
898920-65-5
Product Name Alternative
Cryptochrome protein (CRY)
Purity
98.03% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.01 mM) ; DMSO:30 mg/mL (60.18 mM)
Smiles
O=C1OC2=C (C (OCC (=O) NC=3C=CC=CC3C (=O) N) =CC=4OC (C) (C) CCC42) C (=C1) C=5C=CC=CC5
Molecular Formula
C29H26N2O6
Molecular Weight
498.53
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2-[[2-[(8,8-Dimethyl-2-oxo-4-phenyl-9,10-dihydropyrano[2,3-h]chromen-5-yl)oxy]acetyl]amino]benzamide
CAS Number898920-65-5
PubChem CID4869040
IUPAC Name2-[[2-[(8,8-dimethyl-2-oxo-4-phenyl-9,10-dihydropyrano[2,3-h]chromen-5-yl)oxy]acetyl]amino]benzamide
Molecular FormulaC29H26N2O6
Molecular Weight498.5
XLogP4.4
Topological Polar Surface Area117
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Heavy Atom Count37
Formal Charge0
Complexity910
SMILES
CC1(CCC2=C3C(=C(C=C2O1)OCC(=O)NC4=CC=CC=C4C(=O)N)C(=CC(=O)O3)C5=CC=CC=C5)C
InChI
InChI=1S/C29H26N2O6/c1-29(2)13-12-19-22(37-29)15-23(35-16-24(32)31-21-11-7-6-10-18(21)28(30)34)26-20(14-25(33)36-27(19)26)17-8-4-3-5-9-17/h3-11,14-15H,12-13,16H2,1-2H3,(H2,30,34)(H,31,32)
InChIKey
SVELPNHVEDZZRQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-[[2-[(8,8-Dimethyl-2-oxo-4-phenyl-9,10-dihydropyrano[2,3-h]chromen-5-yl)oxy]acetyl]amino]benzamide
CAS: 898920-65-5
CID: 4869040
Formula: C29H26N2O6
MW: 498.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight498.5
XLogP34.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass498.17908655
Monoisotopic Mass498.17908655
Topological Polar Surface Area117 Ų
Heavy Atom Count37
Formal Charge0
Complexity910
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR18569664CLK2 Antibody
GTR18569618CLK4 Antibody
GTR19219618-01CLK1-IN-3
GTR19212214CLK1-IN-2
GTR17934952CLK2 Antibody
GTR17932887-01CLK2 Antibody
GTR17903907-01CLK1 Antibody
GTR18058163-01CLK4 Antibody
GTR18057847-01CLK2 Antibody
GTR18057845-01CLK1 Antibody

Alternative Products

CatalogName
HY-148765-01CLK8

Popular Products