Products for Research Use Only

BPIQ-I

CAT: 0013-GTR19209761-03Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19209761-03Size:5 mg
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Description
BPIQ-I (PD 159121) is a potent, ATP-competitive inhibitor of the EGFR tyrosine kinase. It demonstrates strong anti-proliferative effects in vitro and has been utilized in research focused on oncology and signal transduction to study EGFR-driven cancer models.
CAS Number
174709-30-9
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.80% (May vary between batches)
Smiles
N (C1=C2C (C=C3C (=C2) N=CN3C) =NC=N1) C4=CC (Br) =CC=C4
Molecular Formula
C16H12BrN5
Molecular Weight
354.2
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Bpiq-i
CAS Number174709-30-9
PubChem CID2427
IUPAC NameN-(3-bromophenyl)-3-methylimidazo[4,5-g]quinazolin-8-amine
Molecular FormulaC16H12BrN5
Molecular Weight354.20
XLogP3.6
Topological Polar Surface Area55.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count22
Formal Charge0
Complexity395
SMILES
CN1C=NC2=C1C=C3C(=C2)C(=NC=N3)NC4=CC(=CC=C4)Br
InChI
InChI=1S/C16H12BrN5/c1-22-9-20-14-6-12-13(7-15(14)22)18-8-19-16(12)21-11-4-2-3-10(17)5-11/h2-9H,1H3,(H,18,19,21)
InChIKey
YAMAGACQNDAKFB-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Bpiq-i
CAS: 174709-30-9
CID: 2427
Formula: C16H12BrN5
MW: 354.20
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight354.20
XLogP33.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass353.02761
Monoisotopic Mass353.02761
Topological Polar Surface Area55.6 Ų
Heavy Atom Count22
Formal Charge0
Complexity395
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes